Comparison of acute appendicitis before and within lockdown period in COVID-19 era: A retrospective study from rural Nepal.
Identifieur interne : 000530 ( Main/Exploration ); précédent : 000529; suivant : 000531Comparison of acute appendicitis before and within lockdown period in COVID-19 era: A retrospective study from rural Nepal.
Auteurs : Suman Baral [Népal] ; Raj Kumar Chhetri [Népal] ; Neeraj Thapa [Népal]Source :
- PloS one [ 1932-6203 ] ; 2021.
Descripteurs français
- KwdFr :
- Adulte (MeSH), Adulte d'âge moyen (MeSH), Appendicectomie (tendances), Appendicite (chirurgie), Appendicite (épidémiologie), Contrôle des maladies transmissibles (méthodes), Durée du séjour (MeSH), Femelle (MeSH), Humains (MeSH), Maladie aigüe (épidémiologie), Mâle (MeSH), Népal (épidémiologie), Pandémies (statistiques et données numériques), Service hospitalier d'urgences (tendances), Sujet âgé (MeSH), Études rétrospectives (MeSH).
- MESH :
- chirurgie : Appendicite.
- méthodes : Contrôle des maladies transmissibles.
- statistiques et données numériques : Pandémies.
- tendances : Appendicectomie, Service hospitalier d'urgences.
- épidémiologie : Appendicite, Maladie aigüe, Népal.
- Adulte, Adulte d'âge moyen, Durée du séjour, Femelle, Humains, Mâle, Sujet âgé, Études rétrospectives.
- Wicri :
- geographic : Népal.
English descriptors
- KwdEn :
- Acute Disease (epidemiology), Adult (MeSH), Aged (MeSH), Appendectomy (trends), Appendicitis (epidemiology), Appendicitis (surgery), COVID-19 (complications), COVID-19 (epidemiology), Communicable Disease Control (methods), Emergency Service, Hospital (trends), Female (MeSH), Humans (MeSH), Length of Stay (MeSH), Male (MeSH), Middle Aged (MeSH), Nepal (epidemiology), Pandemics (statistics & numerical data), Retrospective Studies (MeSH), SARS-CoV-2 (pathogenicity).
- MESH :
- geographic , epidemiology : Nepal.
- complications : COVID-19.
- epidemiology : Acute Disease, Appendicitis, COVID-19.
- methods : Communicable Disease Control.
- pathogenicity : SARS-CoV-2.
- statistics & numerical data : Pandemics.
- surgery : Appendicitis.
- trends : Appendectomy, Emergency Service, Hospital.
- Adult, Aged, Female, Humans, Length of Stay, Male, Middle Aged, Retrospective Studies.
Abstract
INTRODUCTION
The world has been engulfed with the pandemic of the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) which have created significant impact in the emergency surgical health delivery including acute appendicitis. The main aim of this study was to compare the demographic and clinical parameters between two cohorts before the onset of lockdown and within the pandemic.
METHODS
A retrospective analysis was performed between two groups A and B, who presented with acute appendicitis three months prior to and after initiation of lockdown on March 24 2020 respectively in one of the tertiary centers of Nepal. These two cohorts were compared in demographics, clinicopathological characteristics and surgical aspects of acute appendicitis.
RESULTS
There were 42 patients in group A and 50 patients in group B. Mean age of the patients was 31.32±17.18 years with male preponderance in group B (N = 29). Mean duration of pain increased significantly in group B [57.8±25.9(B) vs 42.3±25.0(A) hours, P = 0.004] along with mean duration of surgery [51.06±9.4(B) vs 45.27±11.8(A) minutes, P = 0.015]. There was significant decrease in post-operative hospital stay among group B patients [3.04±1.1(B) vs 3.86±0.67(A) days, P = 0.0001]. Complicated cases increased in group B including appendicular perforation in 10 cases. Similarly, mean duration of presentation to hospital significantly increased in group B patients with perforation [69.6±21.01 vs 51.57±17.63 hours, P = 0.008].
CONCLUSION
During the adversity of the current pandemic, increased number of cases of acute appendicitis can be dealt with surgery as the chances of late presentation and complexity of the lesion exists.
DOI: 10.1371/journal.pone.0245137
PubMed: 33406126
PubMed Central: PMC7787439
Affiliations:
Links toward previous steps (curation, corpus...)
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(chirurgie)</term><term>Appendicite (épidémiologie)</term><term>Contrôle des maladies transmissibles (méthodes)</term><term>Durée du séjour (MeSH)</term><term>Femelle (MeSH)</term><term>Humains (MeSH)</term><term>Maladie aigüe (épidémiologie)</term><term>Mâle (MeSH)</term><term>Népal (épidémiologie)</term><term>Pandémies (statistiques et données numériques)</term><term>Service hospitalier d'urgences (tendances)</term><term>Sujet âgé (MeSH)</term><term>Études rétrospectives (MeSH)</term></keywords><keywords scheme="MESH" type="geographic" qualifier="epidemiology" xml:lang="en"><term>Nepal</term></keywords><keywords scheme="MESH" qualifier="chirurgie" xml:lang="fr"><term>Appendicite</term></keywords><keywords scheme="MESH" qualifier="complications" xml:lang="en"><term>COVID-19</term></keywords><keywords scheme="MESH" qualifier="epidemiology" xml:lang="en"><term>Acute Disease</term><term>Appendicitis</term><term>COVID-19</term></keywords><keywords scheme="MESH" qualifier="methods" 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The main aim of this study was to compare the demographic and clinical parameters between two cohorts before the onset of lockdown and within the pandemic.</p></div><div type="abstract" xml:lang="en"><p><b>METHODS</b></p><p>A retrospective analysis was performed between two groups A and B, who presented with acute appendicitis three months prior to and after initiation of lockdown on March 24 2020 respectively in one of the tertiary centers of Nepal. These two cohorts were compared in demographics, clinicopathological characteristics and surgical aspects of acute appendicitis.</p></div><div type="abstract" xml:lang="en"><p><b>RESULTS</b></p><p>There were 42 patients in group A and 50 patients in group B. Mean age of the patients was 31.32±17.18 years with male preponderance in group B (N = 29). Mean duration of pain increased significantly in group B [57.8±25.9(B) vs 42.3±25.0(A) hours, P = 0.004] along with mean duration of surgery [51.06±9.4(B) vs 45.27±11.8(A) minutes, P = 0.015]. There was significant decrease in post-operative hospital stay among group B patients [3.04±1.1(B) vs 3.86±0.67(A) days, P = 0.0001]. Complicated cases increased in group B including appendicular perforation in 10 cases. Similarly, mean duration of presentation to hospital significantly increased in group B patients with perforation [69.6±21.01 vs 51.57±17.63 hours, P = 0.008].</p></div><div type="abstract" xml:lang="en"><p><b>CONCLUSION</b></p><p>During the adversity of the current pandemic, increased number of cases of acute appendicitis can be dealt with surgery as the chances of late presentation and complexity of the lesion exists.</p></div></front></TEI><pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">33406126</PMID><DateCompleted><Year>2021</Year><Month>01</Month><Day>14</Day></DateCompleted><DateRevised><Year>2021</Year><Month>01</Month><Day>15</Day></DateRevised><Article PubModel="Electronic-eCollection"><Journal><ISSN IssnType="Electronic">1932-6203</ISSN><JournalIssue CitedMedium="Internet"><Volume>16</Volume><Issue>1</Issue><PubDate><Year>2021</Year></PubDate></JournalIssue><Title>PloS one</Title><ISOAbbreviation>PLoS One</ISOAbbreviation></Journal><ArticleTitle>Comparison of acute appendicitis before and within lockdown period in COVID-19 era: A retrospective study from rural Nepal.</ArticleTitle><Pagination><MedlinePgn>e0245137</MedlinePgn></Pagination><ELocationID EIdType="doi" ValidYN="Y">10.1371/journal.pone.0245137</ELocationID><Abstract><AbstractText Label="INTRODUCTION">The world has been engulfed with the pandemic of the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) which have created significant impact in the emergency surgical health delivery including acute appendicitis. The main aim of this study was to compare the demographic and clinical parameters between two cohorts before the onset of lockdown and within the pandemic.</AbstractText><AbstractText Label="METHODS">A retrospective analysis was performed between two groups A and B, who presented with acute appendicitis three months prior to and after initiation of lockdown on March 24 2020 respectively in one of the tertiary centers of Nepal. These two cohorts were compared in demographics, clinicopathological characteristics and surgical aspects of acute appendicitis.</AbstractText><AbstractText Label="RESULTS">There were 42 patients in group A and 50 patients in group B. Mean age of the patients was 31.32±17.18 years with male preponderance in group B (N = 29). Mean duration of pain increased significantly in group B [57.8±25.9(B) vs 42.3±25.0(A) hours, P = 0.004] along with mean duration of surgery [51.06±9.4(B) vs 45.27±11.8(A) minutes, P = 0.015]. There was significant decrease in post-operative hospital stay among group B patients [3.04±1.1(B) vs 3.86±0.67(A) days, P = 0.0001]. Complicated cases increased in group B including appendicular perforation in 10 cases. Similarly, mean duration of presentation to hospital significantly increased in group B patients with perforation [69.6±21.01 vs 51.57±17.63 hours, P = 0.008].</AbstractText><AbstractText Label="CONCLUSION">During the adversity of the current pandemic, increased number of cases of acute appendicitis can be dealt with surgery as the chances of late presentation and complexity of the lesion exists.</AbstractText></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Baral</LastName><ForeName>Suman</ForeName><Initials>S</Initials><Identifier Source="ORCID">0000-0003-0906-138X</Identifier><AffiliationInfo><Affiliation>Department of Surgery, Lumbini Medical College, Tansen, Palpa, Nepal.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Chhetri</LastName><ForeName>Raj Kumar</ForeName><Initials>RK</Initials><AffiliationInfo><Affiliation>Department of Surgery, Lumbini Medical College, Tansen, Palpa, Nepal.</Affiliation></AffiliationInfo></Author><Author 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MajorTopicYN="N">Adult</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D000368" MajorTopicYN="N">Aged</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D001062" MajorTopicYN="N">Appendectomy</DescriptorName><QualifierName UI="Q000639" MajorTopicYN="N">trends</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D001064" MajorTopicYN="N">Appendicitis</DescriptorName><QualifierName UI="Q000453" MajorTopicYN="Y">epidemiology</QualifierName><QualifierName UI="Q000601" MajorTopicYN="Y">surgery</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D000086382" MajorTopicYN="N">COVID-19</DescriptorName><QualifierName UI="Q000150" MajorTopicYN="Y">complications</QualifierName><QualifierName UI="Q000453" MajorTopicYN="N">epidemiology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D003140" MajorTopicYN="N">Communicable Disease Control</DescriptorName><QualifierName UI="Q000379" 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MajorTopicYN="N">Pandemics</DescriptorName><QualifierName UI="Q000706" MajorTopicYN="N">statistics & numerical data</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D012189" MajorTopicYN="N">Retrospective Studies</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D000086402" MajorTopicYN="N">SARS-CoV-2</DescriptorName><QualifierName UI="Q000472" MajorTopicYN="N">pathogenicity</QualifierName></MeshHeading></MeshHeadingList><CoiStatement>The authors have declared that no competing interests exist.</CoiStatement></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="received"><Year>2020</Year><Month>08</Month><Day>07</Day></PubMedPubDate><PubMedPubDate PubStatus="accepted"><Year>2020</Year><Month>12</Month><Day>22</Day></PubMedPubDate><PubMedPubDate PubStatus="entrez"><Year>2021</Year><Month>1</Month><Day>6</Day><Hour>17</Hour><Minute>13</Minute></PubMedPubDate><PubMedPubDate 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